Haematology

Advances in cytogenetics and molecular cytogenetics have shown that although a number of numerical and structural chromosome changes appeared to be random and non-specific, rearrangements involving individual chromosomes were shown to define specific abnormalities in individual cancer types. Fluorescence In Situ Hybridisation (FISH) using locus-specific probes which are capable of defining these stereotypic structural rearrangements has now become a routine diagnostic test in the clinical laboratory. The technique has thus been shown to be useful in the management of cancer patients. Tico Europe offers a range of Cytocell FISH probes specific for a number of haematological malignancies which are available in the Aquarius® liquid format. These probes are directly labelled, ready to use in hybridisation buffer and available in economical 5 and larger 10 test kits.